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How is the regulation of gene expression is influenced by external and internal molecular cues and/or signals?

Topic

Information Flow and Genetics

Framing Question

How is the regulation of gene expression is influenced by external and internal molecular cues and/or signals?

Learning Objectives

  • State the role of a transcriptional repressor (or activator).
  • Define the role of each of the following: promoter region, RNA polymerase, activator binding site, repressor binding site/operator, sigma factor.
  • Describe how bacteria can regulate gene expression at the level of transcription and translation.
  • Explain how gene regulation leads to adaptation.
  • Give examples of how an internal chemical signal can control gene expression.
  • Give examples of how an external chemical signal can control gene expression.
  • Give examples of mechanisms commonly found to regulate the activity of transcription factors, including types of post-translation modification and the binding of small molecule effectors/ligands.

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