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How can cell genomes be manipulated to alter cell function?

Topic

Information Flow and Genetics

Framing Question

How can cell genomes be manipulated to alter cell function?

Learning Objectives

  • List the common features of vectors used for cloning.
  • List one example in medicine or in agriculture when bacteria acquired new genes that resulted in an altered cell function.
  • Describe the mechanisms by which orthologs and paralogs arise.
  • Discuss how horizontal gene exchange contributes to the evolution of a genome and a species.
  • Explain how a transposon can be used to create a mutant strain.
  • Design a vector for a given situation.
  • Discuss two societal benefits achieved through the genetic manipulation of microbes.

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