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Although the central dogma is universal in all cells, how do the processes of replication, transcription, and translation differ in Bacteria, Archaea, and Eukaryotes?

Topic

Information Flow and Genetics

Framing Question

Although the central dogma is universal in all cells, how do the processes of replication, transcription, and translation differ in Bacteria, Archaea, and Eukaryotes?

Learning Objectives

  • State two characteristics of the universal genetic code.
  • State the average size of genes and genomes in a bacterium vs. a human.
  • Explain how chromosome structure differs in Bacteria, Archaea, and Eukaryotes (e.g., histones and circular/linear chromosomes).
  • Explain the role of mRNA processing in Eukaryotes.
  • List the similarities and differences in transcription initiation and termination between Bacteria, Archaea, and Eukaryotes.
  • Explain how the organization of genes in an operon affects transcription in Bacteria, compared to a single gene.
  • List the similarities and differences in translation initiation between Bacteria, Archaea, and Eukaryotes.
  • Present an argument, using the processes of transcription and translation, to explain the evolution of the three Domains: Bacteria, Archaea, and Eukaryotes.
  • Compare and contrast DNA replication in Bacteria, Archaea and Eukaryotes.

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