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How does the structure of the nucleus affect chromosome organization and gene expression?

Topic

Nuclear Structure and Function

Framing Question

How does the structure of the nucleus affect chromosome organization and gene expression?

Learning Objectives

  • Describe the arrangement of chromosomal DNA in the nucleus and how it changes during the cell cycle.
  • Compare and contrast how the presence of a nucleus in eukaryotes and its absence in prokaryotes alters the dynamics of gene expression.
  • Design an experiment to demonstrate the role of the nuclear pore complex.
  • From an evolutionary perspective, propose a mechanism that gave rise to the eukaryotic nucleus.
  • Diagram where ribosomal components are synthesized and where they are assembled.

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