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How is structure (and hence function) of macromolecules governed by foundational principles of chemistry and physics?

Topic

Macromolecular Structure Determines Function and Regulation

Framing Question

How is structure (and hence function) of macromolecules governed by foundational principles of chemistry and physics?

Learning Objectives

  • Relate basic principles of rate laws and equilibria to reactions and interactions and calculate appropriate thermodynamic parameters for reactions and interactions.
  • Explain how a ligand, when introduced to a solution containing a macromolecule to which it can bind, interacts with the macromolecule.
  • Explain, using basic principles, the effects of temperature on an enzyme catalyzed reaction
  • Discuss the dynamic properties of a macromolecule using foundational principles of physics

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